Contact Us

Use the form on the right to contact us.

You can edit the text in this area, and change where the contact form on the right submits to, by entering edit mode using the modes on the bottom right. 

9 Linnell Cir
Billerica, MA, 01821
United States


Parylene Medical Coating - ParyLAST

ParyLAST™ Plasma Enhanced Parylene Medical Device Coating & Surface Treatment

Plasma Enhanced Parylene Coating

ParyLAST™ coatings are:

Conformal:                                                                             Chemically inert:

ParyLAST™ is a tough, pin-hole free coating applicable over                                     ParyLAST™ has superior chemical resistance to nearly all any complex geometry.                                                                                                known solvents.

Tenaciously bonded:                                                            Accepted:

AST’s patented parylene processing techniques                                                      ParyLAST™ has a long history of use and can be found in a
(U.S. Patent Nos. 5,355,832 and 5,447,799) assure superior                                    number of FDA approved implantable devices.
bonding to plastics, glasses, and metals as compared to that
of conventional parylene processing.

Biocompatible:                                                                        Environmentally sound:

ParyLAST™ has demonstrated biocompatibility in long and                                        The ParyLAST™ process is a dry process with no chemical
short-term tests.                                                                                                             waste or residual solvent concerns.


ParyLAST™ has exceptionally high dielectric strength and is thus suitable as an insulating material in medical products.

How is ParyLAST™ different from conventional parylene?

In conventional parylene deposition, parts are first cleaned. Often this cleaning is done with a degreasing solvent. Next, they are soaked in adhesion promoters to improve the inherently poor adhesion of parylene. Lastly, the parylene is vapor deposited on the parts in a vacuum chamber.

ParyLAST™ overcomes parylene’s adhesion limitations by creating molecular level binding between the substrate and the parylene coating. This is achieved by the integration of plasma cleaning and vapor deposition. When parts are to be treated with ParyLAST™, they are placed into the patented reactor. First, they are cleaned and surface activated via a gas plasma molecular activation surface treatment. Then, without breaking containment, parylene is deposited on the surface via the standard vapor-polymerization process. The resulting ParyLAST™ coating, while chemically identical to conventionally applied parylene, is unlike it in that it is a coating with a lifetime resistance to delamination and minimized component failure due to liquid propagation into the coating/substrate interface.

Chemical Resistance

All values are in cm3-mil/100 in2-24hr-atm at 23° C

Nitrogen                    0.95
Oxygen                      7.10
Carbon Dioxide         7.70
Hydrogen Sulfide      13.00
Sulfur Dioxide            11.00
Chlorine                     0.35
Moisture                     0.14 at 37°C and 90%RH

Saline Soak Test







Tenacious Bonding

Method: ASTM D3359-95A “Tape test”

Coating is cut into an “X” or into a crosshatch pattern per protocol. The coating is covered with #810 Scotch Tape and then the tape is pulled off. The degree of coating damage is qualitatively assessed. Zero means removal of the coating beyond the cut area, while 5 means no peeling or removal. Intermediate numbers refer to results between these two extremes. From the data, ParyLAST™ clearly demonstrates superior adhesion.

                                            Conventional Parylene            ParyLAST™

X-Cut pattern                                        0(10 measurements)                                         5(31 measurements)
Cross-Hatch Pattern                             0(16 measurements)                                         5(16 measurements)

Biocompatibility and Sterilization

ParyLAST™ can be sterilized via ETO, gamma radiation, or e-beam sterilization.

ParyLAST™ has passed the following biocompatibility tests:

  • Intracutaneous reactivity
  • Muscle implantation (14 days and 6 months)
  • Systemic toxicity
  • Cytotoxicity
  • Sub-chronic toxicity
  • Hemocompatibility
  • Ames mutagenicity

Electrical Insulation Properties

Dielectric strength, short time (Volts/mil, @ 1 mil)         6800.00
Volume resistivity, 23 C, 50% RH (Ohm-cm)                6.0E+16
Surface resistivity, 23 C, 50% RH (Ohm)                      1.0E+15
Dielectric constant, 60 Hz                                            3.15
Dielectric constant, 1000 Hz                                        3.10
Dissipation factor, 60 Hz                                              0.02
Dissipation factor, 1000 Hz                                          0.02
Dissipation factor, 1,000,000 Hz                                 0.01