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Parylene Medical Coating - ParyLAST

ParyLAST™ Plasma Enhanced Parylene Medical Device Coating & Surface Treatment

ParyLAST™ Plasma Enhanced Parylene Coating


ParyLAST™ coatings are:


ParyLAST™ is a tough, pin-hole free coating applicable over any complex geometry.

Tenaciously Bonded

AST’s patented parylene processing techniques (U.S. Patent Nos. 5,355,832 and 5,447,799) assure superior bonding to plastics, glasses, and metals as compared to that of conventional parylene processing.


ParyLAST™ has demonstrated biocompatibility in long and short-term tests.

Chemically Inert

ParyLAST™ has superior chemical resistance to nearly all known solvents.


ParyLAST™ has a long history of use and can be found in a number of FDA approved implantable devices.

Environmentally Sound

The ParyLAST™ process is a dry process with no chemical waste or residual solvent concerns.


ParyLAST™ has exceptionally high dielectric strength and is thus suitable as an insulating material in medical products.

How is ParyLAST™ different from conventional parylene?

In conventional parylene deposition, parts are first cleaned. Often this cleaning is done with a degreasing solvent. Next, they are soaked in adhesion promoters to improve the inherently poor adhesion of parylene. Lastly, the parylene is vapor deposited on the parts in a vacuum chamber.

ParyLAST™ overcomes parylene’s adhesion limitations by creating molecular level binding between the substrate and the parylene coating. This is achieved by the integration of plasma cleaning and vapor deposition. When parts are to be treated with ParyLAST™, they are placed into the patented reactor. First, they are cleaned and surface activated via a gas plasma molecular activation surface treatment. Then, without breaking containment, parylene is deposited on the surface via the standard vapor-polymerization process. The resulting ParyLAST™ coating, while chemically identical to conventionally applied parylene, is unlike it in that it is a coating with a lifetime resistance to delamination and minimized component failure due to liquid propagation into the coating/substrate interface.


Saline Soak Test

ParyLAST saline soak test table.png

Chemical Resistance

All values are in cm3-mil/100 in2-24hr-atm at 23° C

Nitrogen                    0.95
Oxygen                      7.10
Carbon Dioxide         7.70
Hydrogen Sulfide      13.00
Sulfur Dioxide            11.00
Chlorine                     0.35
Moisture                     0.14 at 37°C and 90%RH

Tenacious Bonding

Method: ASTM D3359-95A “Tape test”

Coating is cut into an “X” or into a crosshatch pattern per protocol. The coating is covered with #810 Scotch Tape and then the tape is pulled off. The degree of coating damage is qualitatively assessed. Zero means removal of the coating beyond the cut area, while 5 means no peeling or removal. Intermediate numbers refer to results between these two extremes. From the data, ParyLAST™ clearly demonstrates superior adhesion.

ParyLAST Adhesion - TaiLei 12pt 600x.jpg

Biocompatibility and Sterilization

ParyLAST™ can be sterilized via ETO, gamma radiation, or e-beam sterilization.

ParyLAST™ has passed the following biocompatibility tests:

  • Intracutaneous reactivity

  • Muscle implantation (14 days and 6 months)

  • Systemic toxicity

  • Cytotoxicity

  • Sub-chronic toxicity

  • Hemocompatibility

  • Ames mutagenicity

Electrical Insulation Properties

ParyLAST Electrical Table - JPG.jpg