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9 Linnell Cir
Billerica, MA 01821
United States

1.978.667.4500

Lubricious & Hydrophilic Medical Coating - LubriLAST

LubriLAST™ Lubricious Hydrophilic Medical Device Coating

Lubricious Hydrophilic Medical Coating

 

LubriLAST™ coatings are:

Aqueous

LubriLAST™ coatings contain no organic solvents. Safer and cleaner manufacturing processes are used, and any concerns about residual solvents in a device are eliminated.

Lubricious

LubriLAST™ coatings virtually eliminate the coefficient of friction in aqueous environments.

 

Biocompatible

LubriLAST™ passes all stringent biocompatibility tests associated with tissue and blood contacting devices.

Accepted

LubriLAST™ is patent protected (US#6,238,799; US#6,866,936) and used in a number of approved devices used in neurovascular, cardiovascular, urological, and surgical applications.

Durable

LubriLAST™ retains its physical integrity and lubricity even after hundreds of cycles.

Flexible

LubriLAST™ withstands use in the tortuous paths found in physiological systems without flaking or delamination. It can be applied to balloons used in a number of medical applications.


How does LubriLAST™ work?

In LubriLAST™, a long chain, bio-compatible hydrophilic polymer is incorporated into the coating. Part of this long hydrophilic polymer becomes entangled with the supporting network while other part remains exposed and able to become hydrated. When in the presence of water or body fluids, the hydrophilic polymer adsorbs water molecules to create a watery interface at the surface of the device. The water cushion reduces wet friction, protein adsorption and cell adhesion.

 

Friction Reduction

Coefficient of friction comparisons*

* Data developed via modified D-1894-95 protocol. Test performed in water, samples pulled against polyethylene.

* Data developed via modified D-1894-95 protocol. Test performed in water, samples pulled against polyethylene.

 

Relative Friction Reduction for Various Substrates:

LubriLAST relative friction bar graph.png

Durability

LubriLAST™ Durability Results After 300 Cycles in Push/Pull Tests:

LubriLAST Durability Graph - less padding.jpg

Biocompatibility

Tissue Biocompatibility

  • Cytotoxicity
  • Sensitization test in guinea pigs
  • Acute intracutaneous reactivity
  • Pyrogen material mediated test
  • Systemic toxicity

 

Hemocompatibilty

  • Direct Hemolysis
  • In vivo thrombogenic resistance study
  • Complement activation
  • Coagulation study

Sterilization and Shelf Life

Medical devices coated with LubriLAST™ can be sterilized by:

  • ETO
  • Gamma
  • E-beam
  • Shelf life: LubriLAST™ sterilized products have a shelf life of 3 years

Datasheet

LubriLAST