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Lubricious & Hydrophilic Medical Coating - LubriLAST

 LubriLAST™ Lubricious Hydrophilic Medical Device Coating

Lubricious Hydrophilic Medical Coating


LubriLAST™ coatings are:


LubriLAST™ coatings contain no organic solvents. Safer and cleaner manufacturing processes are used, and any concerns about residual solvents in a device are eliminated.


LubriLAST™ coatings virtually eliminate the coefficient of friction in aqueous environments.



LubriLAST™ passes all stringent biocompatibility tests associated with tissue and blood contacting devices.


LubriLAST™ is patent protected (US#6,238,799; US#6,866,936) and used in a number of approved devices used in neurovascular, cardiovascular, urological, and surgical applications.


LubriLAST™ retains its physical integrity and lubricity even after hundreds of cycles.


LubriLAST™ withstands use in the tortuous paths found in physiological systems without flaking or delamination. It can be applied to balloons used in a number of medical applications.

How does LubriLAST™ work?

In LubriLAST™, a long chain, bio-compatible hydrophilic polymer is incorporated into the coating. Part of this long hydrophilic polymer becomes entangled with the supporting network while other part remains exposed and able to become hydrated. When in the presence of water or body fluids, the hydrophilic polymer adsorbs water molecules to create a watery interface at the surface of the device. The water cushion reduces wet friction, protein adsorption and cell adhesion.


Friction Reduction

Coefficient of friction comparisons*

 * Data developed via modified D-1894-95 protocol. Test performed in water, samples pulled against polyethylene.

* Data developed via modified D-1894-95 protocol. Test performed in water, samples pulled against polyethylene.


Relative Friction Reduction for Various Substrates:

LubriLAST relative friction bar graph.png


LubriLAST™ Durability Results After 300 Cycles in Push/Pull Tests:

LubriLAST Durability Graph - less padding.jpg


Tissue Biocompatibility

  • Cytotoxicity
  • Sensitization test in guinea pigs
  • Acute intracutaneous reactivity
  • Pyrogen material mediated test
  • Systemic toxicity



  • Direct Hemolysis
  • In vivo thrombogenic resistance study
  • Complement activation
  • Coagulation study

Sterilization and Shelf Life

Medical devices coated with LubriLAST™ can be sterilized by:

  • ETO
  • Gamma
  • E-beam
  • Shelf life: LubriLAST™ sterilized products have a shelf life of 3 years