Lubricious & Hydrophilic Medical Coating - LubriLAST
Lubricious Hydrophilic Medical Coating
LubriLAST™ coatings are:
LubriLAST™ coatings contain no organic solvents. Safer and cleaner manufacturing processes are used, and any concerns about residual solvents in a device are eliminated.
LubriLAST™ coatings virtually eliminate the coefficient of friction in aqueous environments.
LubriLAST™ passes all stringent biocompatibility tests associated with tissue and blood contacting devices.
LubriLAST™ is patent protected (US#6,238,799; US#6,866,936) and used in a number of approved devices used in neurovascular, cardiovascular, urological, and surgical applications.
LubriLAST™ retains its physical integrity and lubricity even after hundreds of cycles.
LubriLAST™ withstands use in the tortuous paths found in physiological systems without flaking or delamination. It can be applied to balloons used in a number of medical applications.
How does LubriLAST™ work?
In LubriLAST™, a long chain, bio-compatible hydrophilic polymer is incorporated into the coating. Part of this long hydrophilic polymer becomes entangled with the supporting network while other part remains exposed and able to become hydrated. When in the presence of water or body fluids, the hydrophilic polymer adsorbs water molecules to create a watery interface at the surface of the device. The water cushion reduces wet friction, protein adsorption and cell adhesion.
Coefficient of friction comparisons*
Relative Friction Reduction for Various Substrates:
LubriLAST™ Durability Results After 300 Cycles in Push/Pull Tests:
- Sensitization test in guinea pigs
- Acute intracutaneous reactivity
- Pyrogen material mediated test
- Systemic toxicity
- Direct Hemolysis
- In vivo thrombogenic resistance study
- Complement activation
- Coagulation study
Sterilization and Shelf Life
Medical devices coated with LubriLAST™ can be sterilized by:
- Shelf life: LubriLAST™ sterilized products have a shelf life of 3 years